PressureWire™ X Guidewire

For Wireless Physiology

PressureWire X Guidewire

Objective Decisions.
Simplified Workflow.

Abbott’s PressureWire™ X Guidewire offers objective decisions with a simplified workflow.

The innovative PressureWire™ X Guidewire—the world’s only wireless physiology wire1—can measure pressure and temperature to calculate Abbott's Resting Full-Cycle Ratio (RFR), Fractional Flow Reserve (FFR), Index of Microcirculatory Resistance (IMR), and Coronary Flow Reserve (CFR). The guidewire’s fully integrated, secure, wireless measurements are integral to a cardiac cath lab’s clinical physiology routine. The PressureWire™ X Guidewire and CoroFlow Cardiovascular System are the only solution for the cath lab able to assess for both epicardial disease and Coronary Microvascular Dysfunction (CMD).2-4

Pressurewire X Guidewire
Pressurewire X Guidewire
Pressurewire X Guidewire

Objective Decisions

  • Innovative sensor housing design offers <1 mmHg/30 min with reduction in drift due to microbubbles5
  • Objective decision-making with both RFR and FFR options
  • RFR has been studied in over 3,500 lesions and 2,000 patients.6-10 Diagnostic equivalence to iFR has been shown in studies such as Re-Validate RFR.9
84% reduced drift with the latest PressureWire X Guidewire compared to its previous sensor housing design

Simplified Workflow

  • The PressureWire™ X Guidewire is the world’s only wireless physiology wire1
  • Wireless: from zero to go in 2 easy steps1
  • Ideal for the modern radial approach­
  • Compatible with the QUANTIEN™ Measurement System and Ultiri™ Measurement System with an easy touchscreen workflow
  • Compatible with CoroFlow Cardiovascular System for a comprehensive physiology assessment
  • Compatible with OPTIS™ Imaging Systems for imaging and physiology needs on one platform
Wireless PressureWire X Guidewire
2 Steps to Connect the Wireless
PressureWire™ X Guidewire1
  1. Zero. Zero the PressureWire™ X Guidewire by turning on the transmitter.
  2. Go. The transmitter’s function indicator shall display a stable green light when it is successfully zeroed.


  1. Volcano Corp. Verrata guidewire and PrimeWire Prestige Plus guidewire Instructions For Use (IFU), Opsens Inc. OptoWire guidewire and OptoWire II guidewire Instructions For Use (IFU), ACIST Medical Systems. Navvus Microcatheter Instructions For Use (IFU), Boston Scientific Corporation. Comet guidewire Instructions For Use (IFU), PressureWire™ X Guidewire Instructions For Use (IFU). Please refer to IFUs for more information.
  2. Data on file at Abbott
  3. Ford TJ, Stanley B, Sidik N, et al. 1-year outcomes of angina management guided by invasive coronary function testing (CorMicA). JACC Intv. 2020; 13:33-45.
  4. Pijls NH, Fearon WF, Tonino PA, et al. Fractional Flow Reserve Versus Angiography for Guiding Percutaneous Coronary Intervention in Patients with Multivessel Coronary Artery Disease. 2-Year Follow-Up of the FAME (Fractional Flow Reserve Versus Angiography for Multivessel Evaluation) Study. JACC. 2010; 56(3): 177-184.
  5. Data on file at Abbott.
  6. Jeremias A, et al. Resting full-cycle ratio (RFR): a novel physiologic index compared to Fractional Flow Reserve (FFR) in assessing the hemodynamic severity of a coronary stenosis: ILUMIEN I + PREDICT. EuroPCR 2018.
  7. Svanerud J, et al. Validation of a novel non-hyperaemic index of coronary artery stenosis severity: the Resting Full-cycle Ratio (VALIDATE RFR) study. EuroIntervention. 2018;14:806-814.
  8. Ahn JM, et al. IRIS FFR: prognostic performance of five resting pressure-derived indexes of coronary physiology. TCT 2018.
  9. Kumar G. et al. Re-Validate Study. CRT 2019.
  10. Lee J-M, et al. Physiological and clinical assessment of resting physiological indexes. Circulation. 2019;139.

MAT-2003659 v2.0