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HeartMate 3 LVAD

With Full Maglev Flow Technology

ARIES-HM3

ARIES-HM3 Outcomes

ARIES-HM3 trial is the first and only international randomized controlled trial to study the effects of avoidance of aspirin on LVAD patients. Trial outcomes demonstrated that avoidance of aspirin in newly implanted adult HeartMate 3™ LVAD patients is safe and significantly reduces the risk of bleeding events.*1

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HeartMate 3 LVAD is a proven long-term, life-extending therapy.2 By avoiding aspirin, outstanding outcomes are made even better.*1

Nearly 40% reduction in GI bleeding events

39%

Reduction in hospitalization days due to bleeding events**

Reduction in hospital stays

Reduction of cost of care for bleeding events**

reduction in cost of care
For more information

For more information on management of hemocompatibility related adverse events and aspirin usage for LVAD patients, read the ISHLT Consensus Statement

Manuals & Resources

Manuals & Resources

Find a HeartMate 3 LVAD Center

Find a HeartMate 3 LVAD Center

*Newly implanted HeartMate 3 LVAD patients. Studied only in patients 18 and over. Decisions regarding the pharmacological management of HeartMate 3 LVAD patients should be individualized by clinicians after fully considering potential risks and benefits

**Based on US patients only.

 

References:

  1. Mehra MR, et al. Aspirin and Hemocompatibility Events With a Left Ventricular Assist Device in Advanced Heart Failure: The ARIES-HM3 Randomized Clinical Trial. JAMA. 2023 Dec 12;330(22):2171-2181. doi: 10.1001/jama.2023.23204. PMID: 37950897; PMCID: PMC10640705
  2. Mehra MR, Goldstein DJ, Cleveland JC, et al. Five-Year Outcomes in Patients With Fully Magnetically Levitated vs Axial-Flow Left Ventricular Assist Devices in the MOMENTUM 3 Randomized Trial. JAMA. September 8, 2022. doi:10.1001/jama.2022.16197

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