Experience the OCT difference.
Request your Abbott Sales rep today.
ILUMIEN IV is the largest global imaging randomized clinical trial with n=2,487 patients in 80 global centers. The trial compared OCT-guided stent implantation vs. angiography guided in high-risk or complex lesions. Primary endpoint was achieving larger post-PCI lumen dimensions and improving clinical outcomes.
OCT-guided PCI significantly reduced stent thrombosis (ST) by 64%
No statistical difference in TVF between OCT-guided and angio-guided PCI at 2 years
OCTOBER trial was conducted in 38 heart centres across 13 European countries with n=1,201 patients randomized in a 1:1 ratio to undergo OCT-guided or angiography-guided PCI of bifurcation coronary lesions. A step-wise protocol was use in the OCT arm; in the angiography arm, intravascular ultrasound use was discouraged but could be pursued for left main (LM) PCI.
The primary endpoint was major adverse cardiac events (MACE), defined as a composite of cardiac death, target lesion myocardial infarction (TL-MI), and ischemia-driven target lesion revascularization (ID TLR), after two years.
OCT-guided PCI of complex bifurcation lesions is superior to angiography-guided PCI for major adverse cardiac events 2 years3
Multiple other studies of OCT-guided PCI vs. angiography alone suggest that intravascular imaging with OCT is associated with better clinical performance3,5,7
|335 pts OCT guided vs 335 pts angio-guided||Reduced rate of cardiac death and MACE in patients who underwent OCT-guided stent intervention.3|
|418 pts||OCT imaging influenced physician decision-making pre-PCI in 57% and post-PCI in 27% of all cases.4|
|450 pts (158 OCT, 146 IVUS, 146 ANGIO)||OCT- guided PCI resulted in superior stent expansion and procedural success compared to angiography-guided PCI.5|
|240 pts NSTEMI||In patients with non-ST-segment elevation acute coronary sydromes, OCT-guided PCI is associated with higher post-procedure FFR than angio-guided PCI.6|
(JACC CARD INT, 2018)
|1,149 pts OCT, 10,971 pts IVUS 75,046 pts angio||OCT-guided PCI was associated with improved procedural outcomes, in-hospital events and long term survival compared with standard angiography-guided PCI.7|
You are about to enter an Abbott country- or region-specific website.
Please be aware that the website you have requested is intended for the residents of a particular country or countries, as noted on that site. As a result, the site may contain information on pharmaceuticals, medical devices and other products or uses of those products that are not approved in other countries or regions
Do you wish to continue and enter this website?