Comparable Results Between OCT and IVUS as Demonstrated in OCTIVUS1


OCT-guided PCI demonstrated comparable results to IVUS-guided PCI at 1 year.1

  • TVF 2.5% OCT vs 3.1% IVUS, p<0.001 for non-inferiority at 1 year
  • Fewer major procedural complications in the OCT group (2.2% vs 3.7%)
  • Reduced procedural time in the OCT group
  • No differences in contrast-related risk between OCT and IVUS


Equals sign

Trial overview:

OCTIVUS trial is an investigator-initiated, prospective, multicenter trial.

  • Conducted at 9 sites in South Korea
  • n=2,008 patients
  • 1:1 randomized ratio to OCT-guided or IVUS-guided PCI

Primary endpoint:

Composite of death from cardiac cause (TV-MI or ID-TVR at one year, powered for non-inferiority of the OCT group as compared with the IVUS group)

OCT vs IVUS Clinical trial chart

Intravascular Ultrasound (IVUS) or Optical Coherence Tomography (OCT)? Let's debate.

Watch Drs. J. Daemen (Rotterdam, NL) and Z. Ali (NY, USA) share their experiences using intravascular imaging technologies in this debate presented at the European Society of Cardiology (ESC) 2023.


  1. Kang D. et al. Optical Coherence Tomography-Guided or Intravascular Ultrasound Guided Percutaneous Coronary Intervention: The OCTIVUS Randomized Clinical Trial, 10.1161/CIRCULATIONAHA.123.066429.

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