CARDIOVASCULAR
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CMD Diagnosis

A Diagnosis of CMD Can Improve Symptoms and Quality of Life

The recent Coronary Microvascular Angina (CorMicA) trial revealed that patients may benefit when coronary microvascular dysfunction is accurately diagnosed and appropriately treated:1

 

27%

IMPROVEMENT IN ANGINA SEVERITY†

sustained angina improvement with cmd treatment
Sustained Angina Improvement with CMD Treatment1,†

† According to the Seattle Angina Questionnaire score.

The CorMicA study data1 reveals that adequate evaluation and optimal treatment of patients who have ischemia with non-obstructive coronary arteries (INOCA) can:

  • Relieve patient symptoms
  • Improve patient quality of life (QOL)
  • Reduce healthcare resource consumption

When patients are diagnosed and treated in fewer cath lab visits, overall healthcare costs may be reduced accordingly.

How to Diagnose CMD with the Coroventis‡ Coroflow‡ Cardiovascular System and PressureWire™ X Guidewire

The PressureWire™ X Guidewire and Coroventis‡ CoroFlow‡ Cardiovascular System can measure both IMR and CFR - allowing for a CMD diagnosis.2

only medical guidewire to diagnose CMD: PressureWire™ X

Pressure and temperature sensors

Angina and negative angiogram could mean CMD

Lee et al. Circ. 2015. *Based on a threshold of IMR > 25 used in Ford, T.J., et al J Am Coll Cardiol Intv. 2020; 13(1):33-45.
Kunadian V, Chieffo A, et al. EHJ & Eurointervention 2020: ehaa503. DOI:10.1093/eurheartj/ehaa503. Knuuti et al. EHJ 2020; 41:407-477. DOI:10.1093/eurheartj/ehz425.
Image adapted from Lee et al, J Am Coll Cardiol 20153

Having a comprehensive physiology testing of both the epicardial arteries and microcirculation can provide clear diagnosis to guide treatment and outcomes.3

How to measure IMR
Allen Jeremias, MD, New York, USA

References

  1. Ford TJ, Stanley B, Sidik N, et al. 1-year outcomes of angina management guided by invasive coronary function testing (CorMicA). J Am Coll Cardiol Intv. 2020;13:33-45.
  2. PressureWire X guidewire IFU. Coroventis CoroFlow Cardiovascular System IFU.
  3. Lee B, Lim H, Fearon WF, et al. Invasive evaluation of patients with angina in the absence of obstructive coronary artery disease. Circulation. 2015;131:1054–1060.
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