To determine the need for percutaneous coronary intervention, fractional flow reserve (FFR) is used to identify functionally significant epicardial coronary stenoses during maximal hyperemia.1
Recording and reviewing FFR measurements is straightforward when using the wireless PressureWire™ X Guidewire.
FFR is a measure of blood pressure difference across a coronary artery stenosis to determine if a stenosis is physiologically significant, which can impede oxygen delivery to the heart muscle.1
Definition of FFR:1
Pd blood flow in stenotic coronary artery
Coronary angiography is not accurate in guiding the functional significance of stenosis in 34% of cases, compared to FFR.2
FFR-guided percutaneous coronary intervention (PCI) leads to a 35% risk reduction in death and myocardial infarction (MI), compared to relying only on angiography.3
Complete revascularization with PressureWire™ X Guidewire led to a 62% relative risk reduction in major adverse cardiac and cerebrovascular events (MACCE) at 1 year.4 The COMPARE-ACUTE trial also revealed that untreated “FFR-positive” non-infarct-related artery lesions are associated with a 31% incidence of MACCE at 1 year.4
|Uses of FFR|
|Left Main Coronary Artery6||-||+++|
|Post-PCI Side Branch Interrogation8||-||+++|
|Uses of Non-Hyperemic Index (RFR)|
|Left Anterior Descending14||+++||++|
|Acute Coronary Syndrome15||+++||++|
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