Structural Interventions

Structural Interventions

The Amplatzer™ portfolio of structural intervention occluders provides minimally invasive treatment options for the closure of congenital heart defects and for stroke risk reduction. The closure procedures are performed through a transcatheter approach, which prevents the need for open heart surgery and enables faster recovery times.

Structural Interventions: Congenital Heart Defects

Amplatzer™ Duct Occluders

The Amplatzer Family of Duct Occluders offers an extensive line of devices and a simple treatment option for the closure of patent ductus arteriosus (PDA). Amplatzer™ Duct Occluders are designed to occlude PDAs of various shapes and sizes. With an easy-to-perform deployment procedure, the implanting physician can be confident in placing the device with precision.

Amplatzer PDA Duct Occluder

Amplatzer™ Septal Occluders

Amplatzer™ Septal Occluders are the standard of care for minimally invasive atrial septal defect (ASD) closure.1,2 These double-disc occluders are comprised of nitinol mesh and polyester material. They are designed to securely appose the septal wall on each side of the defect and create a platform for tissue in-growth after implantation.

Amplatzer™ VSD Occluders

Ventricular septal defects (VSD) are the most commonly found congenital heart defect.3 One subtype of these defects is muscular VSD. If left untreated it can lead to pulmonary hypertension and/or congestive heart failure.4 The Amplatzer™ Muscular VSD Occluders are designed for complete closure of these type of defects.

Structural Interventions: Stroke Risk Reduction

Amplatzer™ Talisman™ PFO Occluder

The Amplatzer™ Talisman™ PFO Occluder set the standard, pioneering treatment with a device developed specifically for patent foramen ovale (PFO) closure to reduce the risk of recurrent ischemic stroke. It’s the leading PFO closure device to date, with over 180,000 devices implanted worldwide.5

Amplatzer Talisman PFO Occluder

Amplatzer™ Amulet™ Left Atrial Appendage Occluder

The Amplatzer™ Amulet™ Left Atrial Appendage Occluder is the only FDA-approved LAA occluder that offers immediate freedom from OACs. With unique dual seal technology to ensure immediate and complete closure and the widest range of sizes of any LAA occluder, Amulet™ makes closure an option for more AFib patients.6

Amplatzer Amulet Occluder

Structural Interventions: Paravalvular Leak

Amplatzer™ Valvular Plug III

The Amplatzer™ Valvular Plug III is specially designed to provide effective closure for patients with a wide range of paravalvular leak morphologies. By providing an effective solution to this key issue, the Amplatzer Valvular Plug III is improving life, quality and longevity to an increasing number of patients.5,6,7,8

Amplatzer Valvular Plug III
Manuals & Technical Resources

Manuals & Technical Resources

Cardiovascular Products

Cardiovascular Products

Customer Service

Customer Service


  1. Kashour TS, Latroche B, Elhoury ME, et al.Successful percutaneous closure of a secundum atrial septal defect through femoral approach in a patient with interrupted inferior vena cava.Congenit Heart Dis.2010;5:620–623.
  2. Tadros VX, Asgar AW.Transcatheter closure of atrial septal defects: an update on ASD occlusion devices.Card Interv Today.2016; March-April.
  3. Hoffman J, Kaplan S. The incidence of congential heart disease. Journal of the American College of Cardiology. 2002;39(12):1890-1900.
  4. Data on file at Abbott.
  5. Calvert et al. Percutaneous device closure of paravalvular leak. Circulation. 2016;134(13):934-944.
  6. Yildirim A, Goktekin O, Gorgulu S, et al. A new specific device in transcatheter prosthetic paravalvular leak closure: a prospective two-center trial. Catheter Cardiovasc Interv. 2016;88(4):618-624.
  7. Smolka G, Pysz P, Kozłowski M, et al. Transcatheter closure of paravalvular leaks using a paravalvular leak device - a prospective Polish registry. Postepy Kardiol Interwencyjnej. 2016;12(2):128-134.
  8. Angulo-Llanos R, Sarnago-Cebada F, Rivera AR, et al. Two-Year Follow Up After Surgical Versus Percutaneous Paravalvular Leak Closure: A Non-Randomized Analysis. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. 2016;88(4):626-634.

MAT-2008012 v3.0 | Item approved for OUS use only.