Advancing the standard of care in peripheral embolization

• A single device solution that allows for faster procedure times, less radiation exposure and lower procedural costs^1,2
• Rapid embolization even in high-flow vessels^1,3,5
• Designed for precise placement, controlled delivery and fully recapturable
• A family of plugs for different vessel conditions
• Limited imaging artifact⁴

Amplatzer™ Vascular Plugs (AVP) Mechanism of Action

The nitinol mesh of an AVP acts as an embolic agent that promotes rapid clot formation. Each AVP creates a physical barrier to blood flow by instigating both the body’s immune response followed by a natural coagulation process.⁶

Intended Purpose

The Amplatzer™ Vascular Plug, Amplatzer™ Vascular Plug II, and Amplatzer™ Vascular Plug 4 are intended for therapeutic embolization to reduce or obstruct blood flow.

Indication for Use

The Amplatzer™ Vascular Plug, Amplatzer™ Vascular Plug II, and Amplatzer™ Vascular Plug 4 are indicated for arterial and venous embolizations in the peripheral vasculature.  

References

1. Pech M, Kraetsch A, Wieners G, et al. Embolization of the Gastroduodenal Artery Before Selective Internal Radiotherapy: A prospectively Randomized Trial Comparing Platinum-Fibered Microcoils with the AMPLATZER Vascular Plug II. CVIR 2009(32)3:455-61.
2. Hart JL, Aldin Z, et al. Embolization of pulmonary arteriovenous malformations using the AMPLATZER vascular plug: successful treatment of 69 consecutive patients. Eur Radiol. 2010;20(11)2663-70.
3. Kucukay F, Özdemir M, Şenol E, Okten S, Ereren M, Karan A. Large pulmonary arteriovenous malformations: long-term results of embolization with AMPLATZER vascular plugs. J Vasc Interv Radiol. 2014 Sep;25(9):1327-32. doi: 10.1016/j.jvir.2014.01.031. Epub 2014 Mar 18.
4. Vandy F, Criado E, Upchurch GR, et al. Translumihnal Hypogastric Artery Occlusion with an Amplatzer Vascular Plug During Endovascular Aortic Aneurysm Repair. J Vasc Surg. 2008; 48(5)1121-4.
5. Data on file at Abbott.
6. Lopera, Jorge E. “The Amplatzer vascular plug: review of evolution and current applications.” Seminars in interventional radiology. Vol. 32. No. 04. Thieme Medical Publishers, 2015.
7. Amplatzer™ Vascular Plug – Instructions for Use (IFU). Refer to IFU for additional information.
8. Amplatzer™ Vascular Plug II – Instructions for Use (IFU). Refer to IFU for additional information.
9. Amplatzer™ Vascular Plug 4 – Instructions for Use (IFU). Refer to IFU for additional information.