CoroFlow Cardiovascular System

The latest v3.6 software, used with the PressureWire™ X Guidewire makes it easier than ever to start doing microvascular assessments1,2

Coroflow Cardiovascular System

Complete Hemodynamic Assessment

With intuitive functionality, the CoroFlow Cardiovascular System with the PressureWire™ X Guidewire provides full physiology data—enabling interventional cardiologists to assess both epicardial vessels and the microvasculature.3-5

CoroFlow v3.6 Software Update Features1

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Routine & Advanced Modes

  • Routine mode simplifies screen and removes research indices
  • Advanced mode same as previous version with research indices
Lock up screen

Results Matrix

  • Result Matrix simplifies result interpretation by facilitating visual representation of indices on 2x2 matrix
  • Three selectable modes:
    • CFR/IMR
    • FFR/IMR
    • FFR/CFR
  • Physiology indices cut-offs:
Cut-off table

*IMR and CFR cutoffs in population of ischemia with no obstructive coronary artery disease (INOCA) patients, CorMicA trial.3

Epicardial Assessment

  • FFR (Fractional Flow Reserve)
  • RFR (Resting Full-Cycle Ratio)—a non-hyperemic index that does not require adenosine infusion
  • Pd/Pa
  • Pullback measurements

Microvascular Assessment

  • CFR (Coronary Flow Reserve)
  • IMR (Index of Microcirculatory Resistance)
  • Pullback CFR
  • RRR (Resistance Reserve Ratio)
  • Absolute flow/resistance

Ventricular Function

  • Contractility, dP/dt
  • Diastolic function
    • EDP (End Diastolic Pressure)
    • Tau (Diastolic Relaxation Constant)

Other Features1


Wireless Communication

When used with the PressureWire™ X Guidewire and Wi-Box™, the CoroFlow Cardiovascular System provides wireless communication, as well as simplified installation and use. The absence of cables means the absence of clutter in the workspace.

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Digital Imaging and Communications in Medicine (DICOM)

Workflow is simplified with the DICOM Worklist. ICs can store both physiologic and angiographic data and images in one archive, e.g., picture archiving and communication system (PACS).

digital imaging

System Use Statistics

Detailed system use statistics; data copied to PC clipboard and saved in log file in system folder.

internet cloud

Cloud-Based Data Management

The system allows for secure remote data access—and multicenter study projects—by using cloud/network data storage.

data management

Automated Study Data Management

Users can rely on greatly simplified study data management and database tools. To ensure data quality control and protection, the system provides built-in review and lock functions, as well as encrypted data storage/user access with Windows 10.

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Multiple Export Options

Calculated measurement parameters and raw waveform data are exported easily into multiple formats and then to USB or cloud/network storage.


  1. CoroFlow Cardiovascular System Instructions for Use (IFU). Refer to IFU for additional information.
  2. PressureWire™ X Guidewire Instructions for Use (IFU). Refer to IFU for additional information.
  3. Ford, TJ., et al., 1-year outcomes of angina management guided by invasive coronary function testing (CorMicA). J Am Coll Card Intu. 2020;13:33-45.
  4. Pijls NH, Fearon WF, Tonino PA, et al. Fractional Flow Reserve Versus Angiography for Guiding Percutaneous Coronary Intervention in Patients with Multivessel Coronary Artery Disease. 2-Year Follow-Up of the FAME (Fractional Flow Reserve Versus Angiography for Multivessel Evaluation) Study. JACC. 2010; 56(3): 177-184.
  5. Data on file at Abbott
  6. Jeremias, A., et al., A test in context: fractional flow reserve: accuracy, prognostic implications, and limitations. J Am Coll Cardiol. 2017;69(22):2748-2758.
  7. Ahn, JM, IRIS-FFR Registry: Prognostic Performance of Five Resting Pressure-Derived Indexes of Coronary Physiology. TCT 2018.

MAT-2114953 v2.0