Using a VCD has several advantages given the following factors during EP procedures such as AF ablations:

• Physicians often have multiple access sites to manage, even some involving large caliber venous sheaths.
• Patients often receive full-dose peri-procedural anticoagulation, and this can make complete hemostasis a challenging and lengthy process, requiring prolonged immobilization.
• The typical EP lab post-procedure process requires the patient to remain immobilized for prolonged periods of time, which is a source of patient discomfort.

All of these issues are mitigated when using the Perclose™ ProStyle™ closure device.

Yes, Same-Day Discharge has been shown to be safe, and it is being used to reduce the total cost of care and to enhance the patient experience. The use of vessel closure devices makes it possible for hospitals to implement Same-Day Discharge.^13,17,18

With the Perclose™ ProStyle™ device you can achieve and confirm complete hemostasis on the table with a suture-mediated repair of the access site. Other advantages of the Perclose ProGlide™ SMC System include:

• The broadest indication* for use in both common femoral veins and arteries
• No ACT-level requirements, so reversal of heparin is not required in order to achieve immediate and durable hemostasis

Find out more about primary healing with the Perclose ProStyle™ vessel closure device.

The Perclose ProStyle™ closure device is indicated for use with:

• Venous sheaths 5-24F¹ (Max. OD 29F¹⁹ / 0.378 inches / 9.59 mm)
• Arterial sheaths 5-21F¹ (Max OD 26F¹⁹ / 0.340 inches / 8.62 mm)

No, there is only one Perclose™ ProStyle™ SMCR System. Multiple Perclose™ ProStyle™ devices can be used, if necessary, for large-bore vascular closure.

Because this device achieves immediate and durable hemostasis, patients can be mobilized and ambulated after approximately two hours (at the physician's discretion). Some facilities have successfully implemented a Same-Day Discharge strategy when using the Perclose™ ProStyle™ SMCR System.

For more details you can read a recent EP Lab Digest article by Sumit Verma, MD, or you can view a Perclose ProGlide™ video featuring Brett Gidney, MD.

It achieves hemostasis by approximating the edges of the vessel wall with a surgical suture, allowing primary intention healing to begin. Primary intention healing minimizes scarring and allows for immediate reaccess if needed. View primary intention healing images with vessel closure device.

Contact your local Abbott representative for a training opportunity.

This is a personal preference. Some operators use caudal to cranial approach—or vice versa—to keep the process consistent.

You can also view one or more physician case recordings using multiple sheaths.

The "Pre-Close" Technique involves the Perclose™ ProStyle™ suture being placed around the access site before the index procedure, and it is required before using sheath sizes > 8F.
See Deployment and Instructions for Use for additional information.

Refer to the Tips and Technique: Poor Flow section of Deployment.

Each Perclose™ ProStyle™ device has a polypropylene monofilament suture with a pre-formed knot which has a tensile strength high enough to approximate the edges of the vessel wall. This suture can snap with quick and jerky movements. You can avoid suture break with the use of slow, consistent, increasing tension. Refer to the Tips and Technique: Suture Break section of Deployment.

Please refer to the Tips and Technique: Cuff Miss section of Deployment.

*As compared to Angio-Seal,^‡ ExoSeal,^‡ FemoSeal,^‡ InClosure,^‡ MANTA,^‡ Mynx,^‡ PerQseal,^‡ Vascade,^‡ Velox CD,^‡ X-Seal^‡. Data on file at Abbott.

1. Abbott Perclose ProGlide Suture-Mediated Closure (SMC) System Instructions for Use.
2. Sekhar A, et al. Femoral arterial closure using ProGlide™ is more efficacious and cost-effective when ambulating early following cardiac catheterization. Int J Cardiol Heart Vasc. 2016;13:6-13. doi: 10.1016/j.ijcha.2016.09.002.
3. 11 million repairs based on Nov. 2021 Finance Report. 27 years based on Nov. 8, 1993 [Perclose] patent was filed for percutaneous suture vascular closure device. The Perclose portfolio includes all percutaneous suture devices. Data on file at Abbott.
4. Gupta S. I Just Need Some Closure: Getting Past Using Manual Compression After Ablation. HRS 2018.
5. Lakshmanadoss U, et al. Figure-of-eight suture for venous hemostasis in fully anticoagulated patients after atrial fibrillation catheter ablation. Indian Pacing Electrophysiol J. 2017;17:134-139. doi: 10.1016/j.ipej.2017.02.003
6. Okada M, et al. Efficacy and safety of figure-of-eight suture for hemostasis after RFCA for AF. Circ J. 2018;82:956-964. doi: 10.1253/circj.CJ-17-1213.
7. Ghannam M, et al. Protamine to expedite vascular hemostasis after catheter ablation of atrial fibrillation: A randomized controlled trial. Heart Rhythm. 2018;15(11):1642-1647. doi: 10.1016/j.hrthm.2018.06.045.
8. Mohanty S, et al. Venous access-site closure with vascular closure device vs. manual compression in patients undergoing catheter ablation or left atrial appendage occlusion under uninterrupted anticoagulation. EP Europace. 2019;21:1048-1054. doi.org/10.1093/europace/euz004.
9. Calkins H, et al. 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation. Heart Rhythm. 2017;14(10):e275-e444. https://dx.doi.org/10.1016/j.hrthm.2017.05.012.
10. Kar, S., et al, The Use of Perclose ProGlide Suture-Mediated Closure (SMC) Device for Venous Access-Site Closure Up to 24F Sheaths. CRT 2018.
11. Mahadaven VS, et al. Pre-closure of femoral venous access sites used for large-sized sheath insertion with the Perclose device in adults undergoing cardiac intervention. Heart. 2008;94:571-572. doi.org/10.1136/hrt.2006.095935.
12. Sairaku A, et al. Rapid hemostasis at the femoral venous access site using a novel hemostatic pad containing kaolin after atrial fibrillation ablation. J Interv Card Electrophysiol. 2011;31:157-164.
13. Verma S. Adopting a strategy of early ambulation and same-day discharge for atrial fibrillation ablation cases. EP Lab Digest. 2019;19(5).
14. Mercandetti M. Wound Healing and Repair. Medscape. Accessed February 26, 2020. https://emedicine.medscape.com/article/1298129-overview
15. Bhatt DL, et al. Successful “pre-closure" of 7Fr and 8Fr femoral arteriotomies with a 6Fr suture-based device (the Multicenter Interventional Closer Registry). Am J Cardiol. 2002;89:777-779.
16. Applies to arterial access.
17. Bartoletti S, Mann M, Gupta A, et al. Same‐day discharge in selected patients undergoing atrial fibrillation ablation. Pacing Clin Electrophysiol. 2019;42:1448-1455.
18. Deyell M, Macle L, Khairy P, et al. The efficacy of a same-day discharge protocol after atrial fibrillation ablation. Canadian J Cardiol. 2018;34:(10 suppl):S84. doi:https://doi.org/10.1016/j.cjca.2018.07.281.
19. Tests performed by and data on file at Abbott.
20. Verma, S., et al, Feasibility and Safety of Same Day Discharge for Patients Undergoing Atrial Fibrillation (AF) Ablation in a Community Hospital Setting. HRS 2020 Science Online, May 2020.