Angiographic assessment alone is not sufficient to diagnose the hemodynamic relevance of epicardial stenosis. Due to its innate limitations, angiography cannot be used to diagnose coronary microvascular dysfunction (CMD).1
This is why growing numbers of societies, thought leaders, and interventional cardiologists (ICs) recommend routine adoption of physiology measurements. The physiology assessment enables ICs to:
PressureWire™ X Guidewire is the only wireless physiology wire that can diagnose both epicardial and microvascular disease.5
View How PressureWire™ X Guidewire Measures FFR, RFR, IMR, and CFR
|Diagnosing Epicardial Stenosis||Diagnosing Coronary Microvascular Dysfunction|
|Guidelines||ACC/SCAI (view here)
CPT code (view here)
|ESC Guideline 2019 (see table below)|
|Cutoff Value||≤ 0.86||≤ 0.897||≥ 254,*||< 2.04,*|
|Formula||Pd/Pa||Lowest Pd/Pa ratio of whole-cycle||Pd/Hyperemic Flow||Hyperemic Flow/Baseline Flow|
*IMR and CFR cutoffs in population of ischemia with no obstructive coronary artery disease (INOCA) patients, CorMicA trial.4
a Class of recommendation. b Level of evidence.
Get the details about measuring each index, below.
With its pressure and temperature sensors, PressureWire™ X Guidewire has the capability to measure the entirety of the coronary circulation:5
PressureWire™ X Guidewire has been extensively studied and clinically validated in both stable and acute coronary syndrome (ACS) patients.9-11
PressureWire™: Nearly 20 Years of Evidence4,8,9,12-32
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