SKIP TO CONTENT
About Abbott
Contact
International | eng
Country Language

CARDIOVASCULAR

International | eng
Country Language

Quadra Allure MP™ CRT-P

HeaderBanner
Clinical Evidence

More Options to Make Non-Response a Non-Issue

The Quadra Allure MP CRT-P brings MultiPoint™ Pacing (MPP), an exclusive Abbott technology, to cardiac resynchronization therapy pacemakers (CRT-Ps).

Overview

MPP technology is designed to deliver multiple independent left ventricular (LV) pacing pulses from a single quadripolar lead to provide you with CRT options to change:

  • Pattern of depolarization
  • Engagement of areas around scar tissue
  • Hemodynamics
  • Resynchronization

Using the Quadra Allure MP CRT-P with Quartet™ quadripolar LV pacing lead, featuring its four pacing electrodes and 14 pacing vectors, provides more options and greater control in CRT response.
 

U.S. IDE Study: Importance of MPP Technology Programming1

The recent IDE study1 post-hoc sub-analysis (n = 199) showed that wider cathode spacing and near-simultaneous intraventricular timing delays provide the best MPP technology response at 87% and “super-response” at 54% (52 patients).1

See details of the U.S. IDE study and other clinical support for MPP.
 

Additional International Clinical Data

This evidence builds on our quadripolar standard of care, which has offered you more options to pace at the preferred LV site, resulting in:

  • Improved CRT outcome2,3
  • Fewer surgical revisions4
  • Reduced need for lead repositioning at implant, leading to shorter procedure times and decreased fluoroscopic exposure5,6
  • More basal pacing opportunities without compromising lead stability7,8


Quadra Allure MP CRT-P Advanced Features and Benefits

Designed to Optimize Tissue Selection

The Quadra Allure MP CRT-P offers Auto VectSelect Quartet™ Test that:

  • Automatically identifies tissue sites with the latest activation via RV-LV conduction delay measurements
  • Performs threshold testing, assesses LVCap™ Confirm applicability and allows marking of PNS

Pacing at the tissue site of latest activation improves:

  • Acute hemodynamic response9
  • Reverse remodeling10
  • Quality of life10

Enhanced Programming Options
  • SyncAV™ CRT technology automatically adjusts pacing based on real-time changes in a patient's cardiac condition

Providing Insightful Diagnostics and Radio Frequency (RF) Monitoring

Quadra Allure MP CRT-P helps you better manage your patients’ heart failure with intuitive programming options and timely access to their vital heart failure diagnostic data through RF monitoring, providing:

  • CorVue™ congestion monitoring for an earlier insight into HF progression
  • Daily remote monitoring of AT/AF alerts for changes in the patient’s AF condition
  • DirectTrend™ reports for a simplified look at all device data

Building Comprehensive Heart Failure Management

The Quadra Allure MP CRT-P is one of our heart failure management therapies. Our vision is to transform the treatment of heart failure by designing technology that delivers excellent clinical outcomes and improves workflow and efficiency. Read more about our approach to heart failure management.

Resources and Documentation

References

  1. Tomassoni, G., Baker II, J., Corbisiero, R., Love, C., Martin, D., Sheppard, R., Worley, S., Varma, N., & Niazi, I. (2016, May). Safety and efficacy of multipoint pacing in cardiac resynchronization therapy: The MultiPoint Pacing (MPP) IDE Study. Presented at the meeting of the Heart Rhythm Society, San Francisco, CA, LBCT 01-03.
  2. Forleo,. G. B., Mantica, M., Di Biase, L., Panattoni, G., Della Rocca, D. G., Papavasileiou, L. P., … Romeo, F. (2012). Clinical and procedural outcome of patients implanted with a quadripolar left ventricular lead: Early results of a prospective multicenter study. Heart Rhythm, 9(11), 1822-1828. https://www.heartrhythmjournal.com/article/S1547-5271(12)00767-9/fulltext
  3. Turakhia, M., Cao, M., Fischer, A., Arnold, E. M., Sloman, L. S., Dalal, N., & Gold, M. (2014, June). Reduced mortality with quadripolar compared to bipolar left ventricular leads in cardiac resynchronization therapy. Presented at the World Congress in Cardiac Electrophysiology and Cardiac Techniques, Nice, France. Retrospective analysis; not prespecified.
  4. Forleo, G. B., Della Rocca, D. G., Papavasileiou, L. P., Molfetta, A. D., Santini, L., & Romeo, F. (2011). Left ventricular pacing with a new quadripolar transvenous lead for CRT: Early results of a prospective comparison with conventional implant outcomes. Heart Rhythm, 8(1), 31-37. https://www.heartrhythmjournal.com/article/S1547-5271(10)01019-2/fulltext
  5. Dänschel, W., Sperzel, J. K., Gutleben, K., Kranig, W., Mortensen, P., Connelly, D., … Hallier, B. (2010). Initial clinical experience with a novel left ventricular quadripolar lead. Europace, 12(Suppl. 1), i127. 
    https://academic.oup.com/europace/article/12/suppl_1/i13/492430
  6. Duray, G. Z., Hohnloser, S. H., Israel, C. W. (2008). Coronary sinus side branches for cardiac resynchronization therapy: prospective evaluation of availability, implant success, and procedural determinants. Journal of Cardiovascular Electrophysiology, 19(5), 489-494. https://onlinelibrary.wiley.com/doi/10.1111/j.1540-8167.2007.01096.x
  7. Merchant, F. M., Heist, E. K., McCarty, D., Kumar, P., Das, S., Blendea, D., … Singh, J. P. (2010). Impact of segmental left ventricular lead position on cardiac resynchronization therapy outcomes. Heart Rhythm, 7(5), 639-644. http://dx.doi.org/10.1016/j.htrhtm.2010.01.035
  8. Singh, J. P., Klein, H. U., Huang, D. T., Reek, S., Kuniss, M., Quesada, A., … Moss, A. J. (2011). Left ventricular lead position and clinical outcome in the Multicenter Automatic Defibrillator Implantation Trial Cardiac Resynchronization Therapy (MADIT-CRT) trial. Circulation, 123(11), 1159-1166. https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.110.000646
  9. Yu, Y., Auricchio, A., Butter, C., Stellbrink, C., Vogt, J., Goehring, A., & Spinelli, J. (2002). Assessment of resynchronization effectiveness of left ventricular lead site. Journal of Cardiac Failure, 8(4S), S72.
  10. Gold, M., Birgersdotter-Green, U., Singh J., Ellenbogen, K., Yu, Y., Meyer, T., …Tchou, P. (2011). The relationship between ventricular electrical delay and left ventricular remodeling with cardiac resynchronization therapy. European Heart Journal, 32(20), 2516-2524. https://academic.oup.com/eurheartj/article/32/20/2516/487679

MAT-2205631 v2.0

POLICIES & ADVISORIES
HEALTHCARE PROFESSIONALS
PATIENTS & CAREGIVERS
Abbott logo

Information contained herein for distribution outside the U.S. only.

CAUTION: These products are intended for use by or under the direction of a physician. Prior to use, reference the Instructions for Use, inside the product carton (when available) or online for more detailed information on Indications, Contraindications, Warnings, Precautions and Adverse Events.

Illustrations are artist's representations only and should not be considered as engineering drawings or photographs.

Unless otherwise specified, all product names appearing in this Internet site are trademarks owned by or licensed to Abbott, its subsidiaries or affiliates. No use of any Abbott trademark, trade name, or trade dress in this site may be made without the prior written authorization of Abbott, except to identify the product or services of the company. ™ Indicates a trademark of the Abbott group of companies. ‡ Indicates a third party trademark, which is property of its respective owner.

© 2025 Abbott. All Rights Reserved.

MAT-2001111 v8.0

Disclaimer

You are about to enter an Abbott country- or region-specific website. 

Please be aware that the website you have requested is intended for the residents of a particular country or countries, as noted on that site. As a result, the site may contain information on pharmaceuticals, medical devices and other products or uses of those products that are not approved in other countries or regions

Do you wish to continue and enter this website? 

YES

MAT-2305078 v1.0