PressureWireTM X Guidewire

for Wireless Physiology


BE CONFIDENT IN YOUR RESTING INDEX DECISION-MAKING with Abbott’s Pressure Wire™ X Guidewire: Abbott’s innovative sensor housing designs offers <1 mmHg/30 minutes with an 84% reduction in drift due to microbubbles.2

Drift is an issue that can lead to misclassification of stenosis.

There are two types of drift: wire-related (true drift) and procedure-related (apparent drift). While there are multiple causes of procedure-related drift, microbubbles (from residual air in device) are a major cause of drift5. Clinically significant drift is classified as ≥3 mmHg1

Drift affects the accuracy of most pressure measurement devices.3 Accuracy is particularly critical for resting indices, as clinical decisions from resting indices are more impacted by drift than FFR4,5. Compared to the hyperemic state, smaller separation between Pa and Pd at rest means it is critical to detect even the slightest difference of pressure.

The Effect of Drift on Stenosis Misclassification by Physiology Index3

Chart showing effect of drift on stenosis misclassification by physiology index

The Distribution of Values for FFR, IFR and Whole-Cycle PD/PA3

Set of charts showing the distribution of values for FFR, IFR and whole-cycle PD/PA


  1. Volcano Corp. Verrata‡ guidewire and PrimeWire Prestige Plus guidewire IFUs, Opsens Inc. OptoWire guidewire and OptoWire II guidewire IFUS, ACIST Medical Systems. Navvus Microcatheter IFU, Boston Scientific Corporation. Comet guidewire IFU, PressureWire™ X guidewire IFU.
  2. Test(s) performed by and data on file at Abbott.
  3. Jeremias, A. et al. A Test in Context: FFR: Accuracy, Prognostic Implications, and Limitations. JACC 2017; 69:2748-58.
  4. Van’t Veer, M. et al. JACC. Comparison of Different Diastolic Resting Indexes to iFR. 70 (25), 2017.
  5. Cook, C. CCI. Quantification of the Effect of Pressure Wire Drift on the Diagnostic Performance of FFR, iFR & Pd/Pa.

MAT-2011811 v1.0


MAT-2103599 v1.0